Men had more early tumor regrowth after full meningioma surgery
Original title: Increased risk of early recurrence after gross-total resection in males with a WHO grade II meningioma: the impact of sex on recurrence and death in 5441 meningioma patients.
How far along is this research?
- Lab cells
- Animals
- Review
- Tested in people
This was tested in people. That is the most reliable kind of research we share.
This looked back at past patient records, not at a new treatment.
The short version
In this study, men with a grade II meningioma had more early regrowth than women.
What was studied. Researchers looked at records of 5441 people with a meningioma brain tumor. All had surgery, and the main group was 4372 people.
What they found. Among people with a CNS WHO grade: A number from 1 to 4 for how a tumor is likely to behave. Since 2021 it is written in plain numbers, not Roman ones. Gene results can set it too. See the glossary II meningioma, men had more early regrowth than women. At 5 years, men had more than two times the risk of the tumor coming back. By 10 years, that difference between men and women was gone.
What this means, and what it doesn't
What it could mean: Men with a grade II meningioma may need close follow-up in the first few years. The study found no clear difference between men and women in the risk of dying. It also found no clear sex difference in grade I tumors.
What it doesn't mean: This does not mean men get worse care or need a different treatment. The study only looked back at past records. So it cannot prove that sex is the reason tumors came back. The authors say the findings need to be checked in other groups. This is not a new treatment, and it is not a cure.
Source: PubMed, September 11, 2026 · Read the original
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