Laser Heat Treatment With Cemiplimab for Glioblastoma That Has Come Back
Original title: Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is a middle stage trial that compares two treatment plans in people.
Status: Not yet recruiting. It has not opened yet. Ask your care team to watch for it if it looks like a fit.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This trial tests laser heat treatment plus cemiplimab against laser heat treatment plus chemotherapy.
Who this trial is for. This trial is for people whose glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary has come back. Everyone gets laser heat treatment, called laser ablation: Using heat from a laser to destroy tumor tissue. The laser goes in through a small hole in the skull, not a large opening. It suits some tumors and not others. Not every hospital offers it. See the glossary. After that, people get either the drug cemiplimab or a chemotherapy drug their doctor picks.
Where it stands. This trial has not reported results. It is measuring how well each of the two treatment plans works. The answer is not in yet.
What this means, and what it doesn't
What it could mean: If your glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary has come back, you could ask your care team about this trial. They can help you see if it might fit your situation. The trial team decides who can join.
What it doesn't mean: This does not mean the treatment is proven. A trial is a test, not care your own doctor can give you. Being in a trial is not a promise that it will help you. It is not a promise of a cure.
Source: ClinicalTrials.gov, October 20, 2026 · Read the original
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