In mice with brain tumors, CBD added nothing to the usual chemo drug
Original title: Exploring the antidepressant-like effects of cannabidiol and/or temozolomide in female mice with induced glioblastoma.
How far along is this research?
- Lab cells
- Animals
- Review
- Tested in people
This was done in animals, not people. Most findings at this stage never become treatments.
This was only done in mice, not in people.
The short version
This was a mouse study, and CBD did not add any benefit to the standard chemo drug.
What was studied. Researchers put brain tumor cells into the brains of female mice. The mice were given temozolomide, the standard chemo drug, with or without CBD, a compound from the cannabis plant.
What they found. Mice given both drugs had smaller tumors. They also showed fewer signs of low mood in stress tests. But mice given the chemo drug alone did just as well, so CBD added nothing.
What this means, and what it doesn't
What it could mean: This says very little about people right now. It hints that the chemo drug itself may affect mood in animals. CBD did not help on top of it in these mice.
What it doesn't mean: This does not mean CBD helps mood in people with brain tumors. The work was done only in mice, which is a very early stage. It is not a cure and it is far from everyday care. Do not add CBD to your treatment because of this study. Talk to your care team first.
Source: PubMed, August 15, 2026 · Read the original
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