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Comparing two ways to give focused radiation to brain tumors that spread from other cancers

Original title: SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

How far along is this research?

This is a trial that is enrolling or has been updated. It is not a finding yet.

This is a middle stage study that compares two treatment plans in people.

Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.

The trial team last updated this record on . Always check the trial page for the latest.

The short version

This study compares one dose of focused radiation with the same treatment split into more than one dose.

Who this trial is for. This trial is for people whose cancer has spread to the brain. It compares focused radiation given in one dose with focused radiation given in more than one dose.

Where it stands. The trial has not reported results. It is looking at how well each way controls the tumor and what side effects people have. The answer is not in yet.

What this means, and what it doesn't

What it could mean: If you have cancer that spread to your brain, this is one study looking at how best to give focused radiation. Someone who fits might ask their care team about it.

What it doesn't mean: This does not mean either way is proven better. A trial is a test, not a proven treatment. Being in a trial is not a promise that it will help you. It is not a cure.

Source: ClinicalTrials.gov, October 1, 2026 · Read the original

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