Comparing gene changes in colorectal cancer that has spread to the brain
Original title: Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
No phase is listed, so this is still a study and not standard care.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study compares gene changes in the first colon tumor and the brain tumor.
Who this trial is for. This study is for people with colorectal cancer that has spread to the brain. It compares the genes KRAS, NRAS, BRAF: A gene in a pathway that tells cells to divide. Some tumors carry a change in it. There are drugs made to target that change, so your team may test for it. See the glossary, HER2, and MSI in pairs of tumor samples.
Where it stands. The study is looking at how well the gene results match between the two tumors. It has not reported results yet. There is no answer from it so far.
What this means, and what it doesn't
What it could mean: This study may show whether the brain tumor needs its own gene test. That answer is not known yet. Someone who fits the study could ask their care team about it.
What it doesn't mean: This does not mean the study has found something. A study is a test, not a proven treatment. Taking part is not a promise that it will help you. It is not a promise of a cure.
Source: ClinicalTrials.gov, October 5, 2026 · Read the original
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