Changes in brain scans may help predict survival in high-grade glioma
Original title: A two-stage model combining clinical and delta-radiomics features for prognosis in high-grade gliomas after chemoradiotherapy: a retrospective study.
How far along is this research?
- Lab cells
- Animals
- Review
- Tested in people
This was tested in people. That is the most reliable kind of research we share.
This used scans from real patients, but the tool is still early and not ready for care.
The short version
Researchers built a computer model that uses brain scans to predict how long patients may live.
What was studied. Researchers looked back at records of 143 people with high-grade glioma: A tumor that starts in the glial cells. Those are the support cells of the brain and spinal cord. Gliomas are given a grade from 1 to 4. The grade says how the tumor is expected to act. See the glossary at two medical centers. All had standard chemotherapy and radiation, with MRI scans taken before and during treatment.
What they found. The model worked best when it mixed scan changes with facts about each patient's health. It did better than models that used scans alone or health facts alone. The team built it with 116 patients, then tested it on 27 patients from another center.
What this means, and what it doesn't
What it could mean: A tool like this might one day help doctors talk about what to expect. That could help with planning. It does not change anyone's treatment today.
What it doesn't mean: This is not a new treatment, and it is not a cure. The study only looked back at old records, so it is early work. The test group was small, just 27 people. One key tumor test was left out of the main model. The model must be checked in larger studies before a doctor could use it. It cannot tell any one person how long they will live.
Source: PubMed, October 14, 2026 · Read the original
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