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Brain tumor death rates stay higher outside big cities

Original title: Urban-Rural Disparities in Malignant Brain Tumour Mortality in the United States, 1999-2020: A CDC WONDER Join point Analysis with Relevance to Neurosurgical Access in Pakistan.

How far along is this research?

This was tested in people. That is the most reliable kind of research we share.

This counted deaths in real people, but it did not test any treatment.

The short version

In the US, people in rural areas died from brain tumors more often than people in big cities.

What was studied. Researchers used US death records from 1999 to 2020. They counted 315,538 brain tumor deaths and sorted them by how rural or city-like each area was.

What they found. In 1999, death rates were lowest in large city centers and highest in rural areas. Per 100,000 people, the rate was 4.34 in large city centers and 4.81 in the most rural areas. The gap was still there in 2020, at 4.08 in large city centers and 4.71 in the most rural areas.

What this means, and what it doesn't

What it could mean: Where you live may shape the care you can reach. Brain surgery and cancer care are mostly in big cities. If you live far from one, ask your doctor about referrals and help with travel.

What it doesn't mean: This does not mean living in a rural area causes a brain tumor death. The study only counted deaths in large groups of people. It cannot show what caused the gap. It is not a treatment, and it is not a cure. It does not change the care you get today.

Source: PubMed, September 1, 2026 · Read the original

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