Brain scans of swelling around meningiomas give only weak clues about tumor grade
Original title: Logarithmic and Conventional MRI Biomarkers of the Tumor-Edema Relationship in Meningioma Derived From Reproducible Volumetric Segmentation.
How far along is this research?
- Lab cells
- Animals
- Review
- Tested in people
This was tested in people. That is the most reliable kind of research we share.
This was a look back at scans people already had, not a new test or treatment you can get.
The short version
Measuring the swelling around a meningioma on MRI gave doctors only a weak hint about how aggressive the tumor was.
What was studied. Researchers looked back at scans from 187 people with a meningioma confirmed by lab testing. Both the tumor and the swelling around it were measured by hand on MRI scans taken before surgery.
What they found. Of the 187 tumors, 145 were grade I and 42 were grade II-III. The measurements based on swelling could tell these groups apart, but only a little. In 51 tumors there was no swelling that could be measured, and 46 of those were grade I.
What this means, and what it doesn't
What it could mean: Swelling around a meningioma may add a small clue about the tumor. It is not accurate enough to replace lab testing of the tumor tissue after surgery. Your care team would still use the full picture, not one measurement.
What it doesn't mean: This does not mean there is a new test you can ask for. This was a look back at old scans at one place, not a trial of a treatment. The measurements were done by hand, and the results were weak. Nothing here is a treatment, and it is not a cure.
Source: PubMed, September 4, 2026 · Read the original
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