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Brain fluid spaces stay changed in shape after surgery for large pituitary tumors

Original title: Statistical Geometric Morphometric Shape Analysis of Ventricular Shape Changes in Giant Pituitary Adenomas Invading the Third Ventricle.

How far along is this research?

This was tested in people. That is the most reliable kind of research we share.

This looked at scans of people who had already had surgery. It is not a new treatment.

The short version

After surgery for a large pituitary tumor, one fluid space deep in the brain stayed changed in shape.

What was studied. Doctors looked at brain scan pictures of people with a large pituitary tumor. All of them had surgery through the nose. The pictures were compared from before surgery, soon after surgery, and later on.

What they found. The third ventricle is a fluid space in the middle of the brain. Its shape changed the most after surgery. That change was still there later on, though it was smaller than the change seen compared with before surgery. The side fluid spaces and one angle the doctors measured did not clearly change.

What this means, and what it doesn't

What it could mean: The deep fluid spaces in the brain may not go back to their old shape after a large pituitary tumor is taken out. The study also suggests that one angle doctors sometimes measure may not be helpful in people whose scans show no sign of fluid buildup.

What it doesn't mean: This does not mean there is a new treatment. It was a study of scan pictures, not a test of a drug or a new kind of surgery. It does not say how any one person will feel or recover. It is not a cure, and it does not change the care a doctor gives today.

Source: PubMed, January 1, 2026 · Read the original

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