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An old drug is being looked at for glioblastoma cells

Original title: Repurposing triamterene to target CLIC1 in glioblastoma stem cells: A new opportunity for an old drug?

How far along is this research?

This was done on cells in a lab, not in people. It is a very early step.

The title points to work on tumor cells, not to treatment in people.

The short version

Researchers are asking if an old drug could act on glioblastoma: A glioma that is given grade 4, the highest grade. It grows fast. Treatment usually starts soon after it is found. It often means surgery, then radiation and chemotherapy. See the glossary stem cells.

What was studied. This item looks at an old drug called triamterene. The question is whether it can act on something called CLIC1 in glioblastoma: A glioma that is given grade 4, the highest grade. It grows fast. Treatment usually starts soon after it is found. It often means surgery, then radiation and chemotherapy. See the glossary stem cells.

What they found. No summary of this work was provided. So the results are not available here. The title ends with a question mark, so it does not state an answer.

What this means, and what it doesn't

What it could mean: Right now this does not change any treatment. It shows that researchers keep testing old drugs for new uses. If you want to know more, ask your care team.

What it doesn't mean: This does not mean triamterene treats brain tumors. The work points at tumor cells, not at people. No details were given here, so there is no proof of any benefit. This is early science, far from everyday care, and it is not a promise of a cure.

Source: PubMed, September 25, 2026 · Read the original

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