Adding flubendazole to standard chemo and radiation for high-grade glioma
Original title: Flubendazole Added to Standard Concurrent Chemoradiotherapy With Temozolomide in Patients With High-Grade Glioma
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This study does not list a phase, so we cannot tell how far along the testing is.
Status: Not yet recruiting. It has not opened yet. Ask your care team to watch for it if it looks like a fit.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study tests adding a drug called flubendazole to the usual treatment for high-grade glioma: A tumor that starts in the glial cells, the support cells of the brain and spinal cord. Gliomas are given a grade from 1 to 4 describing how the tumor is expected to behave. See the glossary.
Who this trial is for. This trial is for people with high-grade glioma: A tumor that starts in the glial cells, the support cells of the brain and spinal cord. Gliomas are given a grade from 1 to 4 describing how the tumor is expected to behave. See the glossary. It tests adding a drug called flubendazole to the usual treatment. The usual treatment here is radiation given along with the chemo drug temozolomide: A chemotherapy taken as a capsule, used for some brain tumors. Your team checks your blood counts while you are on it. See the glossary.
Where it stands. This trial has not reported any results. It is set up to look at how well the added drug works and how safe it is. It also plans to track how long people live, and how long they go without the disease coming back. Those answers are not in yet.
What this means, and what it doesn't
What it could mean: Nothing here changes care today. It does show that doctors are looking at whether this added drug helps. Someone with a high-grade glioma: A tumor that starts in the glial cells, the support cells of the brain and spinal cord. Gliomas are given a grade from 1 to 4 describing how the tumor is expected to behave. See the glossary who thinks they might fit could ask their care team about it. The trial team decides who can join.
What it doesn't mean: This does not mean flubendazole is a proven treatment. A trial is a test. We do not yet know if adding this drug helps, or if it causes harm. Joining a study is not a promise that you will do better. And it is not a promise of a cure.
Source: ClinicalTrials.gov, September 29, 2026 · Read the original
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