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A treatment matched to the genes in a returning glioblastoma

Original title: Pilot Trial for Treatment of Recurrent Glioblastoma

How far along is this research?

This is a trial that is enrolling or has been updated. It is not a finding yet.

This is a first, small test in people.

Status: Enrolling by invitation. It is only taking people the trial team invites. You cannot sign up for this one directly.

The trial team last updated this record on . Always check the trial page for the latest.

The short version

This study tests a treatment chosen from the genes in a person's own tumor.

Who this trial is for. This trial is for 10 adults whose glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary has come back. Each person gets a treatment based on the genes in their own tumor, taken out at surgery.

Where it stands. This trial has not reported results. It is a first look at whether this kind of treatment can be given, and whether a bigger trial is possible. The answers are not in yet.

What this means, and what it doesn't

What it could mean: Doctors are still learning if a treatment matched to your own tumor can work this way. Someone who fits the trial could ask their care team about it.

What it doesn't mean: This does not mean the treatment works. A trial is a test, not proven care. Joining one is not a promise that it will help. It is not a cure.

Source: ClinicalTrials.gov, October 28, 2026 · Read the original

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