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A tissue flap used to close a large skull wound in one operation

Original title: Novel Use of Chimeric Serratus Anterior Fascia-Latissimus Dorsi Flap for Composite Cranial Defect.

How far along is this research?

This was tested in people. That is the most reliable kind of research we share.

This surgery was done in one person and written up as a single case, not tested in a trial.

The short version

Doctors used one surgery to cover a large skull wound in a woman who had a brain tumor and scalp cancer.

What was studied. This is a report about one patient. A 69-year-old woman had a history of a brain tumor called glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary and a fast growing skin cancer on her scalp. Doctors removed the tumor area and rebuilt the site in a single operation.

What they found. The team moved a flap of tissue taken from the back and side of the chest to cover the skull. The flap gave the area several layers of living tissue with its own blood supply. Her recovery went smoothly. At the one year check, the shape of her skull looked good.

What this means, and what it doesn't

What it could mean: Some people need a large part of the scalp and skull rebuilt after surgery. This kind of flap may let doctors do that repair in one operation instead of more than one. The doctors believe it may lower the chance of problems afterward.

What it doesn't mean: This is one person's story, not a study. It does not treat the brain tumor itself, and it is not a cure. One good result cannot tell us how well this works for other people, or who it is safe for. A surgeon would decide if this kind of repair fits a person's own case.

Source: PubMed, March 5, 2026 · Read the original

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