A study of the brain's protective barrier in people with a new glioblastoma
Original title: Characterization of the Blood-Brain Barrier in High-Grade Glioma Through Immunohistochemical, Transcriptional, Fluorescein and Radiological Analyses
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
No phase is listed for this study, and it is gathering information rather than offering a treatment.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study looks at how well the brain's natural barrier is working in people who have just been diagnosed with a brain tumor called glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary.
Who this trial is for. This study is for people newly diagnosed with glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary who are having surgery to remove the tumor. It looks at the blood brain barrier, which is the brain's natural shield, using brain scans, blood tests, thinking and memory tests, and a close look at the tumor tissue taken during the usual surgery.
Where it stands. The study has not reported results. Researchers are still gathering information. They are checking how the shield holds up, how the tumor behaves, and how the brain is working. People take part in checks before surgery, after surgery, and after radiation treatment. The answers are not in yet.
What this means, and what it doesn't
What it could mean: This study is not testing a new treatment. It is trying to understand the tumor and the brain better, which may help guide treatment research later. If you were recently diagnosed with glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary and are facing surgery, you could ask your care team whether a study like this is worth looking into.
What it doesn't mean: This does not mean anything here is a proven treatment. A trial is a test, not care your doctor can give you. Taking part does not guarantee any benefit to you. It is not a promise of a cure.
Source: ClinicalTrials.gov, July 28, 2026 · Read the original
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