A study of blood and tumor samples to learn why glioblastoma comes back
Original title: A Study to Better Understand the Biological and Molecular Mechanisms Involved in Glioblastoma Recurrence and Progression
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
No phase is listed for this study, and it is a study running in people, not care your own doctor can give you.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
Doctors are studying samples from people with glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary to learn what makes the tumor grow back.
Who this trial is for. This study is for people who have had surgery for glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary, either a new diagnosis or a tumor that came back. It uses blood and tumor samples to look at how the body, the immune system, and the tumor behave as the disease returns or gets worse. It is run at one center.
Where it stands. This is a study that collects and studies samples. It is looking at the molecular, immune, and metabolic pathways tied to glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary coming back. No results have been reported. The answers are not in yet.
What this means, and what it doesn't
What it could mean: This study does not test a treatment. It is meant to help doctors understand the disease better, which may help future research. If you have had surgery for glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary and you are being treated at that center, you could ask your care team about it.
What it doesn't mean: This does not mean there is a new treatment. A study is a way to learn, not care that is proven to work. Joining a study is not a guarantee that you will be helped. It is not a promise of a cure.
Source: ClinicalTrials.gov, August 7, 2026 · Read the original
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