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A spinal fluid test to find and track brain lymphoma

Original title: Rapid Diagnosis and Treatment Response Monitoring of Primary CNS Lymphoma Using CSF ctDNA Liquid Biopsy

How far along is this research?

This is a trial that is enrolling or has been updated. It is not a finding yet.

This study does not list a phase, so it is still research and not regular care.

Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.

The trial team last updated this record on . Always check the trial page for the latest.

The short version

This study tests whether a spinal fluid sample can spot brain lymphoma and follow it over time.

Who this trial is for. This trial is for people with a lymphoma that starts in the brain or spinal cord. It tests whether tumor DNA found in spinal fluid can show the cancer and show how it responds to treatment.

Where it stands. The trial has not reported results. The team plans to check more than 100 genes in spinal fluid samples taken at different points in the illness. They also plan to compare those samples with tissue samples. The answer is not in yet.

What this means, and what it doesn't

What it could mean: Getting a piece of the tumor can be hard or risky for some people. A spinal fluid test could be an easier way to get answers sooner. If you think you might fit, you can ask your care team about this study.

What it doesn't mean: A trial is a test, not proven care. Being in one does not mean you will be helped. This is not a promise of a cure. It does not mean this spinal fluid test works better than the usual way of getting a diagnosis.

Source: ClinicalTrials.gov, October 1, 2026 · Read the original

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