A special MRI scan to guide radiation for glioblastoma that has come back
Original title: Spectroscopic MRI, Proton Therapy, and Avastin for Recurrent Glioblastoma
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This study does not list a phase, so we cannot say how far along the testing is.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study is testing whether an experimental MRI scan can help doctors find hidden brain cancer and aim radiation at it.
Who this trial is for. This trial is for people whose glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary has come back. It tests an experimental scan called spectroscopic MRI, which is meant to find hidden cancer. Doctors then use that picture to treat a larger area of the brain with radiation, and to raise the radiation dose. Proton radiotherapy and bevacizumab (Avastin) are used to try to limit side effects.
Where it stands. The trial is still going. It is looking at whether this scan can guide radiation to kill more of the cancer, and whether proton radiotherapy and Avastin keep side effects down. It has not reported results. The answer is not in yet.
What this means, and what it doesn't
What it could mean: If your glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary has come back, this is one place where a different way of planning radiation is being tested. Someone who thinks they might fit could ask their care team about it. The care team can say whether it makes sense for your situation.
What it doesn't mean: This does not mean the approach works. A trial is a test, not a proven treatment. Being in a trial is not a guarantee that it will help you, and it is not a promise of a cure. We also cannot say who will be able to join. That is decided by the trial team.
Source: ClinicalTrials.gov, July 29, 2026 · Read the original
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