A special MRI scan to aim radiation at low oxygen parts of a brain tumor
Original title: Hypoxia-targeted Radiotherapy Boost for GBM
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
No phase is listed for this study, so it is still a test in people.
Status: Not yet recruiting. It has not opened yet. Ask your care team to watch for it if it looks like a fit.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study tests whether a special MRI scan can find low oxygen spots in a brain tumor so radiation can be aimed at them.
Who this trial is for. This study is for people with glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary, a type of brain tumor. It includes people who were just diagnosed, and people whose tumor came back or who have had surgery. It tests a special MRI scan called DSC-MRI that may show tumor areas with low oxygen. It also tests aiming radiation at those areas.
Where it stands. This trial has not reported results. The team wants to learn if the scan really finds the low oxygen areas. They also want to see if radiation aimed this way is safe, and if it helps. Those answers are not in yet.
What this means, and what it doesn't
What it could mean: Doctors think low oxygen areas of a tumor may be harder to treat. This study asks if a scan can spot them and guide radiation there. If you have glioblastoma: The fastest-growing type of glioma (grade 4). Treatment usually starts soon after diagnosis: surgery first, then radiation and chemotherapy. See the glossary, you could ask your care team about this study. They can tell you if it might fit your situation.
What it doesn't mean: This does not mean the scan or the radiation plan is proven. A trial is a test, not treatment you can count on. Joining a study is not a promise that it will help you. It is not a cure, and no one can promise you a spot.
Source: ClinicalTrials.gov, August 18, 2026 · Read the original
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