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A rare type of meningioma found in one dog

Original title: Atypical angiomatous meningioma with E-cadherin-positive inclusion bodies in a dog.

How far along is this research?

This was done in animals, not people. Most findings at this stage never become treatments.

This was microscope work on tissue from one dog, not a treatment tested in people.

The short version

Vets removed a brain tumor from one dog and found unusual clumps inside the tumor cells.

What was studied. An 11-year-old toy poodle was walking oddly. A scan showed a mass near the base of the brain. Surgeons removed it. Then they studied the tissue under microscopes.

What they found. The tumor was a meningioma. It had small nests of tumor cells with a lot of blood vessel tissue between them. Many of the cells held round clumps that pushed the center of the cell to one side. Tests showed these clumps contained a protein called E-cadherin. A stronger microscope showed the clumps were made of folded, membrane-like layers.

What this means, and what it doesn't

What it could mean: For a patient, this does not change anything about care today. It is a single case report in an animal. It adds one small detail to what scientists know about how meningioma cells can look under a microscope.

What it doesn't mean: This is not a treatment and it is not a cure. No drug or therapy was tested here. This was one dog, not a person. The work was done on tissue under a microscope after surgery. That is very far from anything a doctor could offer you.

Source: PubMed, August 6, 2026 · Read the original

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