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A rare brain tumor came back long after surgery

Original title: Intracranial Mesenchymal Tumor with FET-CREB Gene Fusion: A Case Report of Late Recurrence.

How far along is this research?

This was tested in people. That is the most reliable kind of research we share.

This is a report on one patient, not a test of a new treatment.

The short version

One woman's rare brain tumor came back 27 months after surgery removed all of it.

What was studied. Doctors report one patient's case. She was a 58-year-old woman with a rare brain tumor that had a gene change called EWSR1::ATF1.

What they found. Surgery removed the whole tumor, but it came back in the same spot 27 months later. A regular MRI scan found it, and she had no extra treatment in between. A lab test of how fast the cells were growing rose from 5%-10% in the first tumor to 10%-15% in the new one.

What this means, and what it doesn't

What it could mean: This kind of tumor often does well after it is fully removed. Even so, it can come back years later. That is why long-term follow-up scans matter, even when the first signs look good.

What it doesn't mean: This is one patient's story, not a study of many people. It does not tell us how often this tumor comes back. No treatment was tested here, so this is not a new therapy and not a cure. The best follow-up plan and the best extra treatment are still not known.

Source: PubMed, September 29, 2026 · Read the original

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