A radiation implant placed during brain surgery for glioblastoma, compared with usual care
Original title: Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This is a large late stage study, but it is still a test and not care your own doctor can give you.
Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study compares surgery alone with surgery plus a radiation implant for people with glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary.
Who this trial is for. This trial is for people having surgery to remove a glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary. It compares surgery alone with surgery plus GammaTile, a radiation implant placed during the operation.
Where it stands. The trial has not reported results. After surgery, both groups get radiation and chemotherapy taken by mouth. The study team is tracking safety, survival, and how the tumor is doing. The answer is not in yet.
What this means, and what it doesn't
What it could mean: If you are facing surgery for a glioblastoma: A glioma that is given grade 4. Grade 4 is the highest grade there is. The tumor grows fast. Treatment usually starts soon after it is found. It often means surgery, and then radiation and chemotherapy. See the glossary, this is something you could ask your care team about. They know your case and can tell you whether it is worth looking into. The trial team decides who can take part.
What it doesn't mean: This does not mean the implant works better than usual care. A trial is a test, not a proven treatment. Being in one is not a guarantee that it will help you. It is not a promise of a cure.
Source: ClinicalTrials.gov, August 10, 2026 · Read the original
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