A protein in meningioma tissue may signal faster regrowth
Original title: CALB1 expression in meningioma: associations with progression-free survival and chromosome arm 6q loss.
How far along is this research?
- Lab cells
- Animals
- Review
- Tested in people
This was tested in people. That is the most reliable kind of research we share.
This was a look back at tumor tissue from patients, not a test of a treatment.
The short version
A protein found in some meningioma tumors was linked to the tumor growing back sooner.
What was studied. Researchers studied tumor tissue from 147 patients, using 231 small tissue samples. They also checked genes and DNA marks in 110 other meningioma tumors.
What they found. The protein, called calbindin, was found in about 30% of the tumors. Patients with high levels had a shorter time before the tumor grew again. That was also true when the team looked only at grade 2 meningiomas.
What this means, and what it doesn't
What it could mean: A routine lab stain for this protein might help doctors judge risk. It could hint at which meningiomas are more likely to grow back. That may help decide how closely a person is watched.
What it doesn't mean: This is not a treatment, and it is not a cure. It is an early look at stored tumor tissue, not a trial of any drug. The stain is not a standard test in everyday care. Much more work is needed before doctors can rely on it.
Source: PubMed, November 5, 2026 · Read the original
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