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A PET scan tested to tell radiation damage from tumor growth in brain metastases

Original title: Novel Ga68-PSMA PET/CT-tracer to Differentiate Between Radiation Necrosis and Tumor Progression in Brain Metastases

How far along is this research?

This is a trial that is enrolling or has been updated. It is not a finding yet.

The trial does not list a phase, and it is still being studied in people.

Status: Recruiting. It is looking for patients now. Talk to your care team about whether it fits you.

The trial team last updated this record on . Always check the trial page for the latest.

The short version

This trial is testing whether a special scan can tell if a spot in the brain is tumor growth or damage from radiation treatment.

Who this trial is for. This trial is for people with brain metastases from non-small cell lung cancer, melanoma, or breast cancer who have had stereotactic radiation to the brain. It is testing a scan called 68-Gallium PSMA-PET/CT to see how well it can tell radiation damage apart from tumor growth.

Where it stands. There are no results yet. The trial is measuring how well this scan can tell the two things apart. The source does not report any findings, so the answer is not in yet.

What this means, and what it doesn't

What it could mean: After brain radiation, it can be hard to know if a spot on a scan is tumor or damage from the treatment. This trial is looking at one way to answer that. If this sounds like your situation, you could ask your care team about it.

What it doesn't mean: This does not mean the scan works. A trial is a test, not proven care. Joining a trial is not a guarantee that it will help you. It is not a promise of a cure. Only the trial team can decide who takes part.

Source: ClinicalTrials.gov, July 24, 2026 · Read the original

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