A new protein helped mice with brain tumors live longer
Original title: Glioblastoma model mouse rescue from mortality by brain-targeted catalytically-enhanced angiotensin-converting enzyme 2 mutant-antibody fusion protein
How far along is this research?
This is a preprint. Other scientists have not checked it yet, so treat it as an early signal rather than an answer.
This was only tested in mice.
The short version
A new lab-made protein helped mice with brain tumors live longer.
What was studied. Researchers made a protein aimed at the brain, called ACE2dm-s1. They tested it in mice with brain tumors, alone and with another drug.
What they found. Mice lived longer when they got the protein plus the other drug. Neither one on its own helped mice live longer. The protein also changed the immune cells in the brain. It shifted them toward a mix that fights tumors.
What this means, and what it doesn't
What it could mean: This hints at a way to help other cancer treatments work better. Right now it only tells us about mice. No person has been given this protein.
What it doesn't mean: This does not mean a new treatment is ready. The work was done only in mice, which is a very early stage. Many things that help mice do not help people. It is not a cure, and no doctor can offer it today.
Source: bioRxiv (preprint), November 4, 2026 · Read the original
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