A fast gene test during brain surgery to look for leftover IDH1 tumor cells
Original title: Residual IDH1-Mutant Tumor Cell Quantification Study
How far along is this research?
This is a trial that is enrolling or has been updated. It is not a finding yet.
This study lists no phase, and it is still being tried out in people.
Status: Not yet recruiting. It has not opened yet. Ask your care team to watch for it if it looks like a fit.
The trial team last updated this record on . Always check the trial page for the latest.
The short version
This study asks if a quick test during surgery can find tumor cells left behind.
Who this trial is for. This study is for people having surgery for a brain tumor with an IDH gene change: A small change in a tumor's IDH gene. It is the first thing your team looks at when naming an adult glioma, and it can affect which treatments are offered. Your pathology report says whether your tumor has it. See the glossary gene change. It tests a fast gene test used during the operation. The test checks for tumor cells left at the end of surgery. If it finds them, the surgeon may remove more tissue right then.
Where it stands. This study has not reported results. It is measuring whether the fast test can spot leftover IDH gene change: A small change in a tumor's IDH gene. It is the first thing your team looks at when naming an adult glioma, and it can affect which treatments are offered. Your pathology report says whether your tumor has it. See the glossary tumor cells during surgery. It is also looking at whether the test can guide the surgeon in the moment. The answer is not in yet.
What this means, and what it doesn't
What it could mean: If it works, a surgeon could learn during the operation that tumor was left behind. That is not known yet. Everyone in this study gets the test. Someone who may fit could ask their care team about it.
What it doesn't mean: This does not mean the test is proven to help. A trial is a test, not care your doctor can give you today. Being in a trial is not a promise that it will help you. It is not a cure.
Source: ClinicalTrials.gov, September 29, 2026 · Read the original
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