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A device placed in the brain after surgery for high grade glioma, tested with radiation

Original title: Feasibility Assessment of a Medical Device for Tumour Cell Retention and Radiotherapy Sensitization in Patients With Suspected High-grade Glioma

How far along is this research?

This is a trial that is enrolling or has been updated. It is not a finding yet.

This is an early, first look at a new device in people, and no phase was given.

Status: Not yet recruiting. It has not opened yet. Ask your care team to watch for it if it looks like a fit.

The trial team last updated this record on . Always check the trial page for the latest.

The short version

This trial is testing a device called GlioHook that surgeons put in place right after they remove a high grade glioma: A tumor that starts in the glial cells, the support cells of the brain and spinal cord. Gliomas are graded 1 to 4 by how fast they tend to grow. See the glossary.

Who this trial is for. This trial is for people with a suspected high grade glioma: A tumor that starts in the glial cells, the support cells of the brain and spinal cord. Gliomas are graded 1 to 4 by how fast they tend to grow. See the glossary who are having surgery to remove the tumor, followed by standard treatment. It is testing a sterile device called GlioHook that is placed over the edges of the area where the tumor was taken out, with the goal of holding back tumor cells and making radiation work better.

Where it stands. There are no results yet. This is a pilot trial at more than one center, and everyone in it gets the device. The team is checking how safe the device is and looking for early signs of whether it helps. Those answers are not in yet.

What this means, and what it doesn't

What it could mean: For now this means researchers are taking a first look at whether this device is safe to use after brain tumor surgery. Someone facing surgery for a suspected high grade glioma: A tumor that starts in the glial cells, the support cells of the brain and spinal cord. Gliomas are graded 1 to 4 by how fast they tend to grow. See the glossary could ask their care team whether a trial like this fits their situation.

What it doesn't mean: This does not mean the device is a proven treatment. A trial is a test. We do not yet know if it helps, and joining a trial is not a guarantee that you will do better. It is not a promise of a cure.

Source: ClinicalTrials.gov, July 27, 2026 · Read the original

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